Skip to main content
Article thumbnail
Location of Repository

Effects of Lithium on Different Membrane Components of Crayfish Stretch Receptor Neurons

By Shosaku Obara and Harry Grundfest

Abstract

Unlike several other varieties of input membrane, that of the crayfish stretch receptor develops a generator potential in response to stretch when all the Na of the medium is replaced with Li. However, Li depolarizes the receptor neuron, the soma membrane becoming more depolarized than that of the axon. During exposure to Li the cell usually fires spontaneously for a period, and when it becomes quiescent spike electrogenesis fails in the soma but persists in the axon. These effects are seen in the rapidly adapting as well as the slowly adapting cells. The block of spike electrogenesis of the soma membrane is only partly due to the Li-induced depolarization and a significant role must be ascribed to a specific effect of Li

Topics: Article
Publisher: The Rockefeller University Press
OAI identifier: oai:pubmedcentral.nih.gov:2201213
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles

    Citations

    1. (1936). A physiological solution for fresh water crustaceans.
    2. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve.
    3. (1955). a. Processes of excitation in the dendrites and in the soma of single isolated sensory nerve cells of the lobster and crayfish.
    4. (1967). Actions of lithium ions in mammalian sympathetic ganglia.
    5. (1964). Adaptation in stretch receptor neurons of crayfish.
    6. (1955). b. Further study of soma, dendrite, and axon excitation in single neurons.
    7. (1902). Beitr~ige zur allgemeinen Muskel- und Nervenphysiologie. II Mitt. Ueber die Unentbehrlichkeit yon Natrium- (oder Lithium-) Ionen ffir den Contractionsact des Muskels.
    8. (1954). Bioelectric effects of ions microinjected into the giant axon of Loligo.
    9. (1957). Biology and pharmacology of the lithium ion.
    10. (1966). Comparative electrobiology of excitable membranes.
    11. (1967). Crayfish muscle fiber: ionic requirements for depolarizing synaptic electrogenesis.
    12. (1967). Effect of some organic cations on generator potential of stretch receptor of crayfish.
    13. (1967). Effects of lithium on different membrane components in crayfish stretch receptors.
    14. (1955). Effects of some common cations on electroretinogram of the toad.
    15. (1961). Impulse propagation at the septal and commissural junctions of crayfish lateral giant axons, o r.
    16. (1964). Influence of lithium ions on the transmembrane potential and cation content of cardiac cells.
    17. (1961). Ionic mechanisms in electrogenesis.
    18. (1967). Ionic requirements for synaptic electrogenesis in neuromuscular transmission of mealworm larvae (Tenebrio molitor).
    19. (1951). Muscle receptor organs in the abdomen of Homams vulgaris and Palinurus vulgaris.
    20. (1966). Post-tetanic hyperpolarizafion and electrogenic Napump in stretch receptor neurone of crayfish.
    21. (1962). Relation between stimulus strength, generator potential, and impulse frequency in stretch receptor of crustacea.
    22. (1961). Tension changes in crayfish stretch receptors or.
    23. (1963). The effect of changes of the ionic environment upon an isolated crustacean sensory neuron.
    24. (1963). The effect of sodium ion concentration on the eleetroretinogram of the isolated retina of the frog.
    25. (1949). The effect of sodium ions on the electrical activity of the giant axon of the squid.
    26. (1957). The hyperpolarization which follows activity in mammalian non-medullated fibres.
    27. (1955). The nature of the electrochemical potentials of bioelectric tissues.
    28. (1959). The permeability of frog muscle fibres to lithium ions.
    29. (1958). The site of impulse initiation in a nerve cell of a crustacean stretch receptor.
    30. (1965). Voltage clamp experiments on internally perfused giant axons.
    31. (1960). Zur Membranwirkung des Adrenalins auf der Herzmuskelfaser.

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.