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Juvenile iron overload-Advances, but no answers

By Nicole Walker, Darrell Crawford, V. Nathan Subramaniam and Daniel Wallace


Letter to the Editor "I refer to an article published in The Journal in March 1987, in which the authors described a 10-year-old boy with idiopathic hemochromatosis. 1 A liver biopsy showed cirrhosis and parenchymal cell stainable iron grade 4. The hepatic iron concentration was 292.9 μmol/g. Treatment with phlebotomy and desferrioxamine caused the serum ferritin concentration to decrease to 1800 μg/L within 3 months, at which time the case report was published. Recently, the same person—now 29 years old—attended my clinic, and I am pleased to provide further information on the case to your readership. His venesection therapy has continued, and he remains well with a normal serum ferritin concentration and abdominal ultrasound scan...

Publisher: 'Elsevier BV'
Year: 2008
DOI identifier: 10.1016/j.jpeds.2008.06.005
OAI identifier:
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