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ジフテリア・アレルギーに関する実験的研究 第3篇 ジフテリア菌及びジフテリア毒素による皮膚反應に及ぼす免疫血淸の影響



Rabbits inoculated intracutaneously with adequate amounts of diphtheria bacilli or toxin were injected intravenously with immune serum immediately, on the 3rd day, and on the 5th day after inoculation, respectively. In the skin of the animals receiving immune serum immediately after the injection of the toxin, naked eye changes could hardly be observed, though microscopically certain allergic reactions were recognized. In cases in which immune serum was administered on the 3 rd day after the injection of the toxin, the lesions were similar to those of control cases with the exception of a slight allergic reaction, and gross and microscopic differences could hardly be found between the 5th day and control cases. Behaviour of the changes of the skin lesions of the rabbits caused with the bacilli was identical to that with the toxin

Publisher: 札幌医科大学医学部
Year: 1954
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