Ionic current through an open channel:a low-dimensional model of coupling with vibrations of the wall.

Tindjong, R.; Applegate, A.; Eisenberg, R. S.; Kaufman, I.; Luchinsky, D. G.; McClintock, Peter V. E.

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oai:eprints.lancs.ac.uk:31481

Ionic current through an open channel:a low-dimensional model of coupling with vibrations of the wall.

Authors: R. Tindjong
A. Applegate
R. S. Eisenberg
I. Kaufman
D. G. Luchinsky
Peter V. E. McClintock
Publication date: 1 January 2004
Publisher
Doi

Abstract

Ionic motion through an open ion channel is analyzed within the framework of self-consistent Brownian dynamics formalism. A novel conceptual model of coupling of the ion’s motion to the vibrations of the pore walls is introduced. The model allows one to include into simulations an important additional mechanism of energy dissipation and the effects of self-induced strong modulation of the channel conductivity

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