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Oxime Esters of Anthraquinone as Photo-induced DNA-Cleaving Agents for Single- and Double-strand Scissions

By Hwu JR


[[abstract]]Anthraquinone-O-9-(4-cyanobenzoyl)oxime (13) with binding constant of 4.49x 10(4) M-1 exhibited single-strand scission of DNA at the concentration of 10 muM and double-strand scission at 50 muM upon UV irradiation.[[fileno]]2010332010008[[department]]化學

Topics: NUCLEIC-ACIDS, CLEAVAGE, RADICALS, MOIETYanthraquinone, DNA cleavage, photolysis, [[classification]]31
Publisher: Elsevier
Year: 2011
DOI identifier: 10.1016/S0040-4039(03)00375-7
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