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Vaginal yeasts in the era of "over the counter" antifungals

By P.P. Walker, M.T. Reynolds, H.R. Ashbee, C. Brown and E.G.V. Evans

Abstract

OBJECTIVE: To establish whether there has been any rise in the prevalence of non-albicans\ud Candida species isolated from vaginal swabs since the introduction of “over the counter” antifungal\ud treatments.\ud \ud METHOD: A retrospective review looking at all positive vaginal yeast isolates collected from\ud women attending one genitourinary medicine clinic during the 6 year period from 1993 to 1998\ud inclusive. All positive vaginal yeast isolates were included, regardless of whether or not the\ud patients were symptomatic. Isolates from HIV positive women were excluded from the analysis.\ud \ud RESULT: No increase in non-albicans vaginal yeast isolates was shown during the period studied.\ud The proportion of non-albicans yeasts remained constant at approximately 5% of the total yeasts\ud isolated. The most common non-albicans yeast isolated was C glabrata.\ud \ud CONCLUSION: There is no evidence from this study to suggest that the increasing use of “over the\ud counter” antifungal treatment has selected for atypical, possibly inherently azole resistant, strains\ud of vaginal yeasts in HIV seronegative women

Year: 2000
OAI identifier: oai:eprints.whiterose.ac.uk:260

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