A novel equilibrium relating to the helix handedness in G-quadruplexes formed by heterochiral oligonucleotides with an inversion of polarity site

VIRGILIO, ANTONELLA; ESPOSITO, VERONICA; MANGONI, ALFONSO; MAYOL, LUCIANO; GALEONE, ALDO

oai:www.iris.unina.it:11588/563251

A novel equilibrium relating to the helix handedness in G-quadruplexes formed by heterochiral oligonucleotides with an inversion of polarity site

Authors: ANTONELLA VIRGILIO
VERONICA ESPOSITO
ALFONSO MANGONI
LUCIANO MAYOL
ALDO GALEONE
Publication date: 1 January 2013
Publisher
Doi

Abstract

Investigations of heterochiral oligodeoxynucleotides 50-TD1GD2GD3- 30-30-GL3GL2TL1-50 (L33) and 30-TD1GD2GD3-50-50-GL3GL2TL1-30 (L55) forming quadruplex structures are reported. Data indicate the presence of enantiomeric left- and right-handed quadruplex helices. In the case of L55, NMR experiments point to an unusual equilibrium between them

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Archivio della ricerca - Università degli studi di Napoli Federico II

oai:www.iris.unina.it:11588/56...

Last time updated on 12/11/2016

This paper was published in Archivio della ricerca - Università degli studi di Napoli Federico II.

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