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Brain unidentified bright objects ("UBO") in systemic lupus erythematosus: sometimes they come back. A study of microembolism by cMRI and Transcranial Doppler ultrasound

By Alessandra Bortoluzzi, Melissa Padovan, Cristiano Sebastiano Azzini, Alessandro DE VITO, Francesco Trotta and Marcello Govoni


The objectives of this report are to assess the occurrence of microembolic signals (MES) detected by transcranial Doppler ultrasound (TCD) in systemic lupus erythematosus (SLE) patients with (NPSLE) and without (SLE) neuropsychiatric involvement, and to verify the correlation between MES, clinical characteristics, especially the patent foramen ovale (PFO), and the presence of punctuate T2-hyperintense white matter lesions (WMHLs) detected by conventional magnetic resonance imaging (cMRI)

Topics: White matter hyperintense lesions (WMHLs), magnetic resonance imaging (MRI), microembolic signals (MES), patent foramen ovale (PFO), systemic lupus erythematosus (SLE), transcranial Doppler ultrasound (TCD)
Year: 2015
DOI identifier: 10.1177/0961203315608256
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