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Long-lasting CD3(+) T-cell deficiency after cord blood stem cell transplantation in a human herpesvirus 6-infected child

By COMAR M, D'AGARO P, HOREJSH D, GALVAN M, FIORENTINI S, ANDOLINA M, CARUSO A, DI LUCA D. and CAMPELLO C

Abstract

We report a long-lasting (8-month) reactivation of human herpesvirus 6 (HHV-6) infection in child who had undergone cord blood stem cell transplantation. The reactivation was characterized by high viral loads and by immediate-early mRNA positivity. HHV-6 infection was associated with a deep depletion of CD3, while the CD4/CD8 ratio remained substantially unchanged

Year: 2005
OAI identifier: oai:iris.unife.it:11392/1201026
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