In the framework of the project focused on the study of labelling methods of small
biomolecules with novel 99mTc cores, a number of labelling procedures based on the
[99mTc≡N]2+ core have been proposed. It was found that the most useful class of 99mTc
complexes for incorporating small bioactive molecules was that of bis substituted
complexes with bidentate chelating ligands. This class includes both symmetrically and
asymmetrically bis substituted complexes. In symmetrical complexes, two identical
bidentate ligands are coordinated to the same Tc≡N group. Conversely, two different
bidentate ligands bind to the same metal centre in asymmetrical nitrido complexes. In
the paper, a summary of results obtained within the coordinated research project
through the application of the chemistry of 99mTc-nitrido complexes is reported
Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.