Competitive effect of anti-HLA class I monoclonal antibody (01.65) and N-N-staurosporine on prolipherative response of PHA activated T-lymphocytes.

SELVATICI, Rita; RUBINI, Michele; GANDINI, Enrico; ORLANDO P; BALBONI A; BALUGANI S

oai:iris.unife.it:11392/471493

Competitive effect of anti-HLA class I monoclonal antibody (01.65) and N-N-staurosporine on prolipherative response of PHA activated T-lymphocytes.

Authors: Rita SELVATICI
Michele RUBINI
Enrico GANDINI
ORLANDO P
BALBONI A
BALUGANI S
Publication date: 1 January 1991
Publisher: Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: [email protected], INTERNET: http://www.idealibrary.com, Fax: (407)352-3445

Abstract

N-N-Staurosporine (STAR) inhibits in a dose dependent manner Tritiated-Thymidine (3H-TdR) incorporation in phytohemagglutinin (PHA) activated Peripheral Blood Mononuclear Cells (PBMC) treated with anti-HLA class I monoclonal antibody (MAb) 01.65 and its effect results competitive with MAb 01.65. Cytosolic and particulate Protein Kinase C (PKC) have been studied. Only when PKC particulate activity is no more detectable, the effect of STAR on 3H-TdR incorporation is evident

info:eu-repo/semantics/article

Similar works

Full text

Archivio istituzionale della ricerca - Università di Ferrara

oai:iris.unife.it:11392/471493

Last time updated on 12/11/2016

This paper was published in Archivio istituzionale della ricerca - Università di Ferrara.

Having an issue?

Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.