A facile, efficient synthesis of 2-substituted-4-hydroxy-2-cyclopenten-1-ones

Abstract

4-​Bromocyclopentenones I [R = Br, R1 = H, Me, MeO2CCH2, MeO2C(CH2)​6] underwent solvolysis in refluxing H2O or H2O-​dioxane to give 63-​71​% I (R = HO, R1 = same)​. Similarly, 41-​57​% I (R = MeO, R1 = same) were were obtained by solvolysis of I (R = Br) in refluxing MeOH

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Archivio istituzionale della ricerca - Università di Ferrara

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Last time updated on 12/11/2016

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