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Imaging of carotid plaque angiogenesis

By E. VICENZINI, GIANNONI MF, F. BENEDETTI-VALENTINI and GL LENZI

Abstract

Display Settings:AbstractFormat SummarySummary (text)AbstractAbstract (text)MEDLINEXMLPMID ListApplySend to:Choose DestinationFileClipboardCollectionsE-mailOrderMy Bibliography Format Summary (text)Abstract (text)MEDLINEXMLPMID ListCSV Create File 1 selected item: 19372660 Format SummarySummary (text)AbstractAbstract (text)MEDLINEXMLPMID ListMeSH and Other Data E-mail Additional text E-mail "SPAM" filtering software notice Add to Clipboard Add to Collections Order articles Add to My Bibliography Cerebrovasc Dis. 2009;27 Suppl 2:48-54. Epub 2009 Apr 16. Imaging of carotid plaque angiogenesis. Vicenzini E, Giannoni MF, Benedetti-Valentini F, Lenzi GL. SourceDepartment of Neurological Sciences, Sapienza University of Rome, Rome, Italy. edoardo.vicenzini@uniroma1.it Abstract Currently, characterization of the vulnerable plaque is a hot research topic as a more adequate strategy for preventing cerebrovascular events is being sought. Histological studies have recognized that plaque inflammation and the presence of adventitial vasa vasorum, intimal angiogenesis and plaque neovascularization are strong predictors of instability in atheromatous lesions of cerebrovascular and cardiovascular patients. The in vivo study of these features has been the focus of development of several new radiological imaging methods. Carotid ultrasound, with ultrasound contrast agents, is not only able to provide an enhanced assessment of the arterial lumen and plaque morphology with an improved resolution of the carotid intima-media thickness, but also to directly visualize adventitial vasa vasorum and plaque neovascularization. This technique and its future clinical implications are discussed in the present review. Copyright 2009 S. Karger AG, Basel. PMID: 19372660 [PubMed - indexed for MEDLINE

Topics: Conmtrast enhanced ultrasound Imaging, carotid plaque, angiogenesis
Publisher: Karger
Year: 2009
DOI identifier: 10.1159/000203126
OAI identifier: oai:iris.uniroma1.it:11573/228338
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