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Analysis of functional variants reveals new candidate genes associated with alexithymia

By Massimo Mezzavilla, Sheila Ulivi, Martina La Bianca, Davide Carlino, Paolo Gasparini and Antonietta Robino

Abstract

In this study we explored the possible association between 36,915 functional variants and alexithymia, a personality trait characterized by the inability to identify and describe emotions and feelings. From our analysis, variants in the genes ABCB4, TP53AIP1, ARHGAP32 and TMEM88B were identified linked to the alexithymia phenotype

Topics: ABCB4, Alexithymia, Functional variants, Adolescent, Adult, Affective Symptoms, Aged, Case-Control Studies, DNA-Binding Proteins, Female, Humans, Male, Membrane Proteins, Middle Aged, P-Glycoproteins, Personality Inventory, Phenotype, Tumor Suppressor Proteins, Young Adult, Emotions, Psychiatry and Mental Health, Biological Psychiatry, Medicine (all)
Year: 2015
DOI identifier: 10.1016/j.psychres.2015.03.018
OAI identifier: oai:arts.units.it:11368/2881241
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