Antimycobacterial activity of new N1-[1-[1-aryl-3-[4-(1H-imidazol-1-yl)phenyl]-3-oxo]propyl]-pyridine-2-carboxamidrazone derivatives

ZAMPIERI, DANIELE; MAMOLO, MARIA GRAZIA; VIO, LUCIANO; ROMANO, MAURIZIO; Skoko, Nataša; Baralle, Marco; Pau, Valentina; Logu, Alessandro De

oai:arts.units.it:11368/2875602

Antimycobacterial activity of new N1-[1-[1-aryl-3-[4-(1H-imidazol-1-yl)phenyl]-3-oxo]propyl]-pyridine-2-carboxamidrazone derivatives

Authors: DANIELE ZAMPIERI
MARIA GRAZIA MAMOLO
LUCIANO VIO
MAURIZIO ROMANO
Nataša Skoko
Marco Baralle
Valentina Pau
Alessandro De Logu
Publication date: 1 January 2016
Publisher
Doi

Abstract

N1-[1-[1-aryl-3-[4-(1H-imidazol-1-yl)phenyl]-3-oxo]propyl]-pyridine-2-carboxamidrazone derivatives were design, synthesized and tested for their in vitro antimycobacterial activity. The new compounds showed a moderate antimycobacterial activity against the tested strain of Mycobacterium tuberculosis H37Ra and a significant antimycobacterial activity against several mycobacteria other than tuberculosis strains

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Archivio istituzionale della ricerca - Università di Trieste

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Last time updated on 12/11/2016

This paper was published in Archivio istituzionale della ricerca - Università di Trieste.

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