Electron transport through quantum-dot (QD) cascades was investigated using the formalism of nonequilibrium Green's functions within the self-consistent Born approximation. Polar coupling to optical phonons, deformation potential coupling to acoustic phonons, as well as anharmonic decay of longitudinal optical phonons were included in the simulation. A QD cascade laser structure comprising two QDs per period was designed and its characteristics were simulated. Significant values of population inversion enabling lasing in the terahertz frequency range were predicted, with operating current densities being more than an order of magnitude smaller than in existing terahertz quantum-well-based quantum-cascade lasers
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