Skip to main content
Article thumbnail
Location of Repository

Synthetic metallomolecules as agents for the control of DNA structure

By Adair D. Richards and Alison Rodger

Abstract

This tutorial review summarises B-DNA structure and metallomolecule binding modes and illustrates some DNA structures induced by molecules containing metallic cations. The effects of aquated metal ions, cobalt amines, ruthenium octahedral metal complexes, metallohelicates and platinum complexes such as cis-platin are discussed alongside the techniques of NMR, X-ray crystallography, gel electrophoresis, circular dichroism, linear dichroism and molecular dynamics. The review will be of interest to people interested in both DNA structure and roles of metallomolecules in biological systems

Topics: QD, QR
Publisher: Royal Society of Chemistry
Year: 2007
OAI identifier: oai:wrap.warwick.ac.uk:2189

Suggested articles


To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.