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A novel codon insert in protease of clade B HIV type 1.

By Parris S Jordan, Art Poon, Joseph Eron, Kathleen Squires, Caroline Ignacio, Douglas D Richman and Davey M Smith

Abstract

A novel combination of three codon inserts in the pol coding region of HIV-1 RNA was identified in a highly antiretroviral experienced study subject with HIV-1 infection. A one codon insert was observed in the protease region between codon 40 and 41 simultaneously with a two codon insert present in the reverse transcriptase region at codon 69

Topics: Division of Infectious Diseases and Environmental Medicine, Thomas Jefferson University, Base Sequence, HIV Infections, HIV Protease, HIV Reverse Transcriptase, HIV-1, Humans, Models, Molecular, Molecular Sequence Data, Mutagenesis, Insertional, RNA, Viral, Sequence Analysis, DNA, Models, Molecular, Mutagenesis, Insertional, RNA, Viral, Sequence Analysis, DNA, Infectious Disease
Publisher: Jefferson Digital Commons
Year: 2009
OAI identifier: oai:jdc.jefferson.edu:didem-1002

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