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A Comparison of Objectively- and Subjectively-Measured Adherence in Glaucoma Patients of African Descent

By Nabeel Awan, Ankita Sutaria, Silvia M. Bigatti, Emily Sirk, Elizabeth Hosty, Chloe Payton, Shelbi Grow, Bradley Sutton, Julie Torbit and Lyne Racette


poster abstractPurpose. Adherence to medical treatment of glaucoma is challenging. People of African descent (AD) have higher prevalence of open-angle glaucoma (OAG) and have been shown to have worse adherence. The goal of this prospective, observational study was to compare objectively- and subjectively-measured adherence in patients of African descent and to determine their relationship with self-efficacy. Methods. Twenty-one patients of AD diagnosed with OAG in the past five years were included in this study. Patients used a once-daily topical prostaglandin analog eye drop and self-administered their medication. Subjective adherence was assessed through self-report. Adherence was objectively measured using MEMS bottles. The cap of these bottles records the number of times the bottle is opened. Self-efficacy was assessed using the 10-item Glaucoma Medication Self-Efficacy scale and the 6-item Eye Drop Technique Self-Efficacy scale. MEMS adherence percentages were compared to self-reported adherence using a paired sample two-tailed t-test. To assess the relationship between objectively measured adherence and self-efficacy, patients were divided into 3 groups (n=7 each): high, medium and low adherence groups. The Chi-square test was used to determine whether differences in self-efficacy between the groups were present for each question on the two self-efficacy scales. Results. Subjectiveadherence (mean ± standard deviation) (97.34% ± 5.61) was significantly higher than objective adherence (66.34% ± 26.68) (p= 0.01). Of the 21 patients, 17 self-reported higher adherence levels than MEMS adherence levels. 4 patients with the highest levels of objectively measured adherence were the only patients to correctly estimate their adherence by self-report. Only one question was significantly associated with objective adherence: patients with high adherence were significantly more confident about taking their glaucoma medications when they do not experience symptoms (p = 0.04). Conclusions. Results showed that patients with higher adherence are more confident about using their eye drops in the absence of symptoms

Topics: People of African descent (AD), open-angle glaucoma (OAG), glaucoma, adherence, self-efficacy
Publisher: Office of the Vice Chancellor for Research
Year: 2015
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Provided by: IUPUIScholarWorks

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