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The oncogenic potential of Epstein-Barr virus nuclear antigen 1 in transgenic mice

By J.B. Wilson and A.J. Levine


The human herpes virus, Epstein-Barr virus (EBV) is highly prevalent among all communities. Although largely asymptomatic prior to puberty it is the etiologic agent of the lymphoproliferative disorder, infectious mononucleosis. The virus is also tightly associated with two major forms of human B-cell malignancy: endemic Burkitt’s lymphoma (BL) and the lymphomas to which immunosupressed individuals are prone (for review see Epstein and Achong, 1986)

Publisher: Springer
Year: 1992
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Provided by: Enlighten
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