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A non-nucleoside triphosphate for powering kinesin-microtubule motility with photo-tunable velocity

By Nishad Perur, Masao Yahara, Takashi Kamei and Nobuyuki Tamaoki


Three non-nucleoside triphosphates, one containing an azobenzene moiety, power a kinesin-microtubule system with high motile activity, with an observed maximum velocity of almost half of that obtained with ATP. The cis–trans photoisomerization of the azobenzene unit allows reversible and repeated control over the motile properties of kinesin

Topics: 430
Publisher: Royal Society for Chemistry
Year: 2013
DOI identifier: 10.1039/c3cc45933k
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