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Using the Man9(GlcNAc)2 – DC-SIGN pairing to probe specificity in photochemical immobilization

By Suzanne J. Dilly, Andrew J. Clark, Daniel A. Mitchell, Andrew Marsh and Paul C. Taylor

Abstract

We demonstrate the expected preference of an immobilised oligosaccharide Man(9)(GlcNAc)(2) upon a 96-well photochemical array, for its known receptor, the cell-surface lectin Dendritic Cell-Specific ICAM3 Grabbing Nonintegrin (DC-SIGN) when compared to immobilised competing monosaccharides

Topics: QD
Publisher: Royal Society of Chemistry
Year: 2011
OAI identifier: oai:wrap.warwick.ac.uk:3197

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