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Tracking Parkinson's Disease over One Year with Multimodal Magnetic Resonance Imaging in a Group of Older Patients with Moderate Disease

By T.R. Melzer, D.J. Myall, M.R. MacAskill, T.L. Pitcher, L. Livingston, R. Watts, R.J. Keenan, J.C. Dalrymple-Alford and T.J. Anderson

Abstract

Background & Objectives: Cross-sectional magnetic resonance imaging (MRI) suggests that Parkinson’s disease (PD) is associated with changes in cerebral tissue volume, diffusion tensor imaging metrics, and perfusion values. Here, we performed a longitudinal multimodal MRI study—including structural, diffusion tensor imaging (DTI), and perfusion MRI—to investigate progressive brain changes over one year in a group of older PD patients at a moderate stage of disease

Topics: Field of Research::11 - Medical and Health Sciences::1109 - Neurosciences, Field of Research::17 - Psychology and Cognitive Sciences::1701 - Psychology::170101 - Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology), Field of Research::11 - Medical and Health Sciences::1103 - Clinical Sciences::110320 - Radiology and Organ Imaging
Publisher: University of Canterbury. Psychology
Year: 2015
OAI identifier: oai:ir.canterbury.ac.nz:10092/12358
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