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Rheumatology International

By Fernando Glasner Araújo, Tiago Nardi Amaral, Simone Appenzeller and Jozélio Freire de Carvalho


Texto completo: acesso restrito. p. 1721-1724The aim of this study was to evaluate the frequency of seizures in systemic sclerosis (SSc) and to determine the clinical and laboratory features associated with their occurrence. Thirty-four SSc patients (ACR criteria) were analyzed by a standard interview, physical examination, and review of medical charts. Risk factors for seizures, clinical manifestations, associated co-morbidities and current treatment were evaluated. We identified 3 (8.8 %) SSc patients with seizures. A higher median age [61 (35–64) vs. 48 (27–71) years, p = 0.0005] and higher activity score [4.75 (4.5–5.0) vs. 2.5 (0–5–5) years, p = 0.006] were observed in SSc patients with seizures. No other clinical or laboratory feature was associated with the occurrence of seizure in this cohort. This study demonstrated a higher prevalence of seizures in SSc when compared to general population. Seizures were associated with older age and higher activity score in this cohort

Topics: Seizures, Epilepsy, Convulsion, Systemic sclerosis, Scleroderma
Year: 2014
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