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Microarray Data Interpretation

By Petr Ludwig


This Bachelor thesis explains the basics of biochip or microarray data interpretation, starting with short introduction to genetics, especially genetic information significance evaluating. The focus was set mainly on the set of scripts transforming and analyzing the sample data. The data used in this thesis are a result of biochip analysis of the Colon Tumor tissues. The secondary result represents disclosing the main marker for this particular type of cancer, the primary result is evaluation of marker significance in the context of signaling pathways. The resulting pathways are sorted by relevance

Topics: biochip; cancer; gene ontology; rakovina; signaling pathways; colon; genes expression; tlusté střevo; genetika; upregulation; up regulace; genetics; microarray; exprese genů; genové signální dráhy; downregulation; Ruby; KEGG; down regulace; DNA; Desmin; nukleové kyseliny; bioinformatics; nucleus acids; genová ontologie; karcinom; geny; RNA; biočip; tumor; BioRuby; bioinformatika
Publisher: Vysoké učení technické v Brně. Fakulta informačních technologií
Year: 2008
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