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Scaling of arterial input function in DCE-MRI

By Tomáš Holeček


Perfusion magnetic resonance imaging is modern diagnostic method used mainly in oncology. In this method, contrast agent is injected to the subject and then is continuously monitored the progress of its concentration in the affected area in time. Correct determination of the arterial input function (AIF) is very important for perfusion analysis. One possibility is to model AIF by multichannel blind deconvolution but the estimated AIF is necessary to be scaled. This master´s thesis is focused on description of scaling methods and their influence on perfussion parameters in dependence on used model of AIF in different tissues

Topics: multichannel blind deconvolution; scaling; DCE-MRI; perfusion analysis; Magnetická rezonance; multikanálová slepá dekonvoluce; TRF; perfusní analýza; škálování; dynamic contrast enhanced magnetic resonance imaging; impulse response function; Magnetic resonance imaging; AIF; arterial input function
Publisher: Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií
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