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Effects of diabetes family history and exercise training on the expression of adiponectin and leptin and their receptors

By Colin N. Moran, Nicholas D. Barwell, Dalia Malkova, Steve J. Cleland, I. McPhee, Christopher J. Packard, V. A. (Victor A.) Zammit and J. M. R. (Jason M. R.) Gill

Abstract

The daughters of patients with diabetes have reduced insulin sensitivity index (ISI) scores compared with women with no family history of\ud diabetes, but their ISI increase more in response to exercise training(1). The present study aimed to determine whether differences between\ud these groups in exercise-induced changes in circulating adiponectin and leptin concentrations and expression of their genes and receptors\ud in subcutaneous adipose tissue (SAT), could explain differences in the exercise-induced changes in ISI between women with and without\ud a family history of diabetes

Topics: RC
Publisher: Cambridge University Press
Year: 2009
OAI identifier: oai:wrap.warwick.ac.uk:4448

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