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Differential expression of immune defences is associated with specific host-parasite interactions in insects

By Carolyn Riddell, Sally Adams, Paul Schmid-Hempel and Eamonn B. Mallon

Abstract

Recent ecological studies in invertebrates show that the outcome of an infection is dependent on the specific pairing of\ud host and parasite. Such specificity contrasts the long-held view that invertebrate innate immunity depends on a broadspectrum\ud recognition system. An important question is whether this specificity is due to the immune response rather than\ud some other interplay between host and parasite genotypes. By measuring the expression of putative bumblebee\ud homologues of antimicrobial peptides in response to infection by their gut trypanosome Crithidia bombi, we demonstrate\ud that expression differences are associated with the specific interactions

Topics: QL
Publisher: Public Library of Science
Year: 2009
OAI identifier: oai:wrap.warwick.ac.uk:4538

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