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Changes in the BCG-Induced T cell response over the first year of life

By Andreia Soares

Abstract

Includes bibliographical references (leaves 190-238).Bacille Calmette-Guerin (BCG), the only currently available tuberculosis vaccine, is the most widely administered vaccine in the Expanded Programme on Immunisation (EPI). Despite this, many gaps in our knowledge of BCG-induced T cell responses exist. The primary objective of this study was to comprehensively delineate T cell immunity induced by BCG vaccination of newborns and to longitudinally assess BCG-specific T cell responses over the first year of life

Topics: Tuberculosis, BCG vaccination
Publisher: Department of Paediatrics & Child Health
Year: 2011
OAI identifier: oai:open.uct.ac.za:11427/14310

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