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Regression of an asymptomatic choroidal metasta- sis from breast carcinoma following letrozole therapy*

By Jayshan Yohendran and Devinder Chauhan


<p>Background: Uveal metastases are commonly of breast origin, typically affecting the posterior choroid. Treatment of such uveal tumours can lead to significant ocular side effects.</p><p>Methods: We present the clinical and optical coherence tomography findings of a patient with an asymptomatic choroidal metastases.</p><p>Results: A 62-year-old lady presented with an asymptomatic uniocular choroidal metastases from breast origin. She was being treated with letrozole, a nonsteroidal aromatose inhibitor, for known pleural metastases. The choroidal lesion was inactive at presentation to our clinic and required no further treatment.</p><p>Conclusion: The use of letrozole can lead to choroidal metastasis regression.</p

Topics: Choroidal metastasis, letrozole, breast carcinoma, aromatase inhibitors, Ophthalmology, RE1-994
Publisher: AOSIS
Year: 2009
DOI identifier: 10.4102/aveh.v68i4.165
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