Skip to main content
Article thumbnail
Location of Repository

Efficacy of the porcine species in biomedical research

By Karina eGutierrez, Naomi eDicks, Werner Giehl Glanzner, Luis B Agellon and Vilceu eBordignon


Since domestication, pigs have been used extensively in agriculture and kept as companion animals. More recently they have been used in biomedical research, given they share many physiological and anatomical similarities with humans. Recent technological advances in assisted reproduction, somatic cell cloning, stem cell culture, genome editing and transgenesis now enable the creation of unique porcine models of human diseases. Here we highlight the potential applications and advantages of using pigs, particularly minipigs, as indispensable large animal models in fundamental and clinical research, including the development of therapeutics for inherited and chronic disorders, and cancers

Topics: Biomedical Research, Swine, pigs, Clones, transgenics, large animal models, Genetics, QH426-470
Publisher: Frontiers Media S.A.
Year: 2015
DOI identifier: 10.3389/fgene.2015.00293
OAI identifier:
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • (external link)
  • (external link)
  • (external link)
  • Suggested articles

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.