Skip to main content
Article thumbnail
Location of Repository

MicroRNAs in the host-Apicomplexan parasites interactions: a review of immunopathological aspects

By Carla Cristina Judice, Catarina eBourgard, Ana Carolina Andrade Vitor Kayano, Letusa eAlbrecht and Fabio Trindade Maranhão Costa

Abstract

MicroRNAs (miRNAs), a class of small non-coding regulatory RNAs, have been detected in a variety of organisms ranging from ancient unicellular eukaryotes to mammals. They have been associated with numerous molecular mechanisms involving developmental, physiological and pathological changes of cells and tissues. Despite the fact that miRNA-silencing mechanisms appear to be absent in some Apicomplexan species, an increasing number of studies have reported a role for miRNAs in host-parasite interactions. Host miRNA expression can change following parasite infection and the consequences can lead, for instance, to parasite clearance. In this context, the immune system signaling appears to have a crucial role

Topics: Apicomplexa, Parasites, microRNA, immune response, host cell, Microbiology, QR1-502
Publisher: Frontiers Media S.A.
Year: 2016
DOI identifier: 10.3389/fcimb.2016.00005
OAI identifier: oai:doaj.org/article:ccdc1a20f0de41658d4f29ee0219acce
Journal:
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • https://doaj.org/toc/2235-2988 (external link)
  • http://journal.frontiersin.org... (external link)
  • https://doaj.org/article/ccdc1... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.