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DETECTION OF IMMUNOGLOBULINS, ANTIBODIES TO HEAT-SHOCK PROTEINS AND IL-8 CYTOKINE IN SALIVA FROM THE PATIENTS WITH CHRONIC PERIODONTAL DISEASES

By N. N. Tsybikov, Y. I. Pinelis, M. S. Malezik and L. P. Malezik

Abstract

Examination of the patients with chronic generalized periodontitis revealed a sufficient increase in all immunoglobulin classes, i.e., IgG, IgM, IgA, sIgA, as well as increased IL-8 concentration in their salivary samples. Emergence of antibodies to heat-shock proteins suggests a pathogenetic role of chaperon-like proteins in development of periodontal diseases

Topics: heat-shock proteins, immunity, immunoglobulin, periodontitis, Immunologic diseases. Allergy, RC581-607
Publisher: SPb RAACI
Year: 2010
OAI identifier: oai:doaj.org/article:8fd6dbb26f744b07813ca3e14ae27ac1
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