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CHOICE OF TARGETED DRUG FOR SECOND-LINE METASTATIC COLON CANCER CHEMOTHERAPY

By M. Yu. Fedyanin, A. A. Tryakin and S. A. Tjulandin

Abstract

<p><em>Durin</em><em>g the last 5 years the prognosis of metastatic colorectal cancer patients improved significantly. This results not only from increased amount of surgery for metastatic disease and use of targeted drugs in first-line treatment, but also from increased number of patients receiving effective second- and third-line chemotherapy. Currently a minimum of 7 treatment groups can be distinguished depending on prior first-line chemo- and targeted therapy. Consequentially we have less evidence-based data to guide the treatment choice for next treatment lines. This article discusses the choice of targeted drugs in combination with second-line chemotherapy.</em></p

Topics: метастатический рак толстой кишки, вторая линия химиотерапии, таргетная терапия, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Publisher: ABV-press
Year: 2015
OAI identifier: oai:doaj.org/article:8f60beb7b146430590b529055851c0b5
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