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Clinicopathologic analysis of lethal influenza cases in 2009–2011

By S. A. Gladkov, I. V. Grigorieva, V. A. Dedov, E. V. Esaulenko and V. A. Zinserling

Abstract

<p>The authors conducted clinicopathologic analysis of 33 cases of lethal influenza caused mainly by influenza virus H1N1/California in northwest regions of Russia. Five types of structural changes in lungs were outlined: 1) massive serous-hemorrhagic edema (9% of studied cases); 2) serous and desquamative viral pneumonia (6%); 3) viral pneumonia with acute phase of diffuse alveolar damage (DAD) (18%); 4)viral pneumonia with prevalence of regenerative and hyperplastic changes (27%); 5) mixed viral and bacterial pneumonia (36%). The authors also made morphological description of two types of virus-induced cytopathic changes (two types of «influenza»-cells).</p

Topics: грипп, летальные исходы, клинико- морфологические сопоставления, Infectious and parasitic diseases, RC109-216
Publisher: Journal Infectology
Year: 2011
OAI identifier: oai:doaj.org/article:6fc2fa95f6f34f99bf84cb59854f05ed
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