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Features of the oxidation processes and state of microcirculatory channel have persons exposed to low doses of ionizing radiation

By Ya. V. Porovsky, T. V. Zhavoronok, N. V. Ryazntseva and F. F. Tetenev

Abstract

<p class="a">We have examined 36 liquidators (participants in emergency clean-up after the Chernobylnuclear accident) many years after the external γ-irradiation (on average (143.0 ± 14.0) mGy for (3.3 ± 0.8) months) and 13 workers of a typical research nuclear reactor, who were subject to chronic external γ-irradiation (on average (78.40 ± 12.21) mGy for (13.1 ± 2.2) years). The level of metabolites of lipid peroxidation (conjugated diene and triene conjugates of lipid hydroperoxides, TBA-reactive products) and the activity of catalase, superoxide dismutase, 5'-nucleotidase in blood serum were determined; changes in vessels of microcirculatory bloodstream (MCB) in skin-muscle bioptate were analyzed. Under the action of small doses of ionizing radiation, the oxidative disbalance and changes in activity of 5'-nucleotidase in blood serum сaccompanying the systematic inflammatory alteration of MCB vessels were found.<strong></strong></p

Topics: микроциркуляторное русло, малые дозы ионизирующего излучения, окислительный дисбаланс, Medicine, R
Publisher: Siberian State Medical University (Tomsk)
Year: 2012
OAI identifier: oai:doaj.org/article:4249a8b479fd41308c2859bc41018c98
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