In outpatient practice, neurologists often face patients diagnosed with dyscirculatory encephalopathy (DEP). Sleep disorders, headaches, rapid and unexplained fatigability, and irritability are predominating, which poses a number of complex medical issues. A case report of a 69 year-old patient, who was being followed up for a long time because of DEP diagnosis is reported. However, examination of the neu-ropsychic status revealed the depressive disorder with somatoform complaints, which was verified by a psychiatrist. Psychotherapy and antidepressant therapy led to significant improvement. The differential diagnosis and treatment of depressive disorders in outpatient practice are discussed
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