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Chemo selective one-pot synthesis of 2-aryl-1-arylmethyl-1H-benzimidazoles using Amberlite IR-120

By Shivraj Hariram Nile, Brajesh Kumar and Se Won Park


A simple, efficient and eco-friendly one pot synthesis method has been developed for ultrasound induced synthesis of biologically significant 2-aryl-1-arylmethyl-1H-benzimidazoles in EtOH/H2O solvent mixture using Amberlite IR-120. The catalyst is recyclable without loss of activity. The method provides several advantages such as green solvent, simple work-up procedure, shorter reaction time and higher yield

Topics: Benzimidazoles, Amberlite IR-120, One-pot reaction, Ultrasound irradiation, Chemistry, QD1-999
Publisher: Elsevier
Year: 2015
DOI identifier: 10.1016/j.arabjc.2012.12.006
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