Skip to main content
Article thumbnail
Location of Repository

A classification system for tableting behaviors of binary powder mixtures

By Changquan Calvin Sun

Abstract

The ability to predict tableting properties of a powder mixture from individual components is of both fundamental and practical importance to the efficient formulation development of tablet products. A common tableting classification system (TCS) of binary powder mixtures facilitates the systematic development of new knowledge in this direction. Based on the dependence of tablet tensile strength on weight fraction in a binary mixture, three main types of tableting behavior are identified. Each type is further divided to arrive at a total of 15 sub-classes. The proposed classification system lays a framework for a better understanding of powder interactions during compaction. Potential applications and limitations of this classification system are discussed

Topics: Powder, Mixture, Tensile strength, Tabletability, Classification system, Compaction, Therapeutics. Pharmacology, RM1-950
Publisher: Elsevier
Year: 2016
DOI identifier: 10.1016/j.ajps.2015.11.122
OAI identifier: oai:doaj.org/article:835f77d3f162415491bf841ce9495404
Journal:
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • https://doaj.org/toc/1818-0876 (external link)
  • http://www.sciencedirect.com/s... (external link)
  • https://doaj.org/article/835f7... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.