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An Update on Inflamm-Aging: Mechanisms, Prevention, and Treatment

By Shijin Xia, Xinyan Zhang, Songbai Zheng, Ramin Khanabdali, Bill Kalionis, Junzhen Wu, Wenbin Wan and Xiantao Tai

Abstract

Inflamm-aging is a challenging and promising new branch of aging-related research fields that includes areas such as immunosenescence. Increasing evidence indicates that inflamm-aging is intensively associated with many aging diseases, such as Alzheimer’s disease, atherosclerosis, heart disease, type II diabetes, and cancer. Mounting studies have focused on the role of inflamm-aging in disease progression and many advances have been made in the last decade. However, the underlying mechanisms by which inflamm-aging affects pathological changes and disease development are still unclear. Here, we review studies of inflamm-aging that explore the concept, pathological features, mechanisms, intervention, and the therapeutic strategies of inflamm-aging in disease progression

Topics: Immunologic diseases. Allergy, RC581-607
Publisher: Hindawi Publishing Corporation
Year: 2016
DOI identifier: 10.1155/2016
OAI identifier: oai:doaj.org/article:b17e509aa5e640789b5fd398d05c89d9
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