Skip to main content
Article thumbnail
Location of Repository

PF573,228 inhibits vascular tumor cell growth, migration as well as angiogenesis, induces apoptosis and abrogates PRAS40 and S6RP phosphorylation

By Mabeta Peace

Abstract

PF573,228 is a compound that targets focal adhesion kinase (FAK), a non-receptor protein kinase, which is over-expressed in various tumors. The aim of this study was to evaluate the effects of PF573,228 on the cells derived from mouse vascular tumors, namely, endothelioma cells

Topics: PF573,228, focal adhesion kinase, endothelioma, apoptosis, angiogenesis, Pharmaceutical industry, HD9665-9675
Publisher: De Gruyter Open
Year: 2016
DOI identifier: 10.1515/acph-2016-0031
OAI identifier: oai:doaj.org/article:e17d04c4d5224207a0cf4135975e6d77
Journal:
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • https://doaj.org/toc/1846-9558 (external link)
  • http://www.degruyter.com/view/... (external link)
  • https://doaj.org/article/e17d0... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.