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Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib

By Darrell C. Bessette, Erik Tilch, Tatjana Seidens, Michael C. J. Quinn, Adrian P. Wiegmans, Wei Shi, Sibylle Cocciardi, Amy McCart-Reed, Jodi M. Saunus, Peter T. Simpson, Sean M. Grimmond, Sunil R. Lakhani, Kum Kum Khanna, Nic Waddell, Fares Al-Ejeh and Georgia Chevenvix-Trench

Abstract

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Topics: Growth factor receptor, Amino acid substitution, Affect protein function, Acute myeloid leukaemia (AML), Kinase gene complex, 1100 Agricultural and Biological Sciences, 1300 Biochemistry, Genetics and Molecular Biology
Publisher: Public Library of Science
Year: 2015
DOI identifier: 10.1371/journal.pone.0125232
OAI identifier: oai:espace.library.uq.edu.au:UQ:360241

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