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Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome

By Giustina Ferone, Helen A. Thomason, Dario Antonini, Laura De Rosa, Bing Hu, Marica Gemei, Huiqing Zhou, Raffaele Ambrosio, David P. Rice, Dario Acampora, Hans van Bokhoven, Luigi Del Vecchio, Maranke I. Koster, Gianluca Tadini, Bradley Spencer-Dene, Michael Dixon, Jill Dixon and Caterina Missero

Abstract

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Topics: AEC syndrome, epidermis, FGF signalling, p63 knock-in, p63 target genes, GROWTH-FACTOR RECEPTOR, HAY-WELLS-SYNDROME, STEM-CELLS, EPIDERMAL MORPHOGENESIS, EPITHELIAL DEVELOPMENT, CRUCIAL ROLE, P53 HOMOLOG, ANKYLOBLEPHARON, HAIR, SKIN, 313 Dentistry
Publisher: 'Wiley'
Year: 2012
DOI identifier: 10.1002/emmm.201100199
OAI identifier: oai:helda.helsinki.fi:10138/161933
Journal:

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