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Oesophageal Cancer: Staging, Surgery and Survival

By A.K. (Aaldert) Talsma

Abstract

Many improvements have been made in the treatment of oesophageal\ud cancer. Surgical techniques have been refined, multimodality treatment\ud has become the standard of care and nationwide quality audits\ud have been introduced. Nevertheless, there are some persevering challenges\ud in the treatment of oesophageal cancer and its complications:\ud 1. with current staging modalities, even after radical surgery, many patients\ud suffer from early recurrence (“challenge to stage”) ; 2. more than\ud half of the patients who undergo surgery will still die from oesophageal\ud cancer (“challenge to cure”) ; 3. complications after surgery cannot\ud always be treated early and appropriately (“challenge to rescue”) ; 4.\ud surgery alone, without preceding neoadjuvant therapy, too often has\ud the disadvantage of involved surgical resection margins (“challenge\ud to resect”); 5. there is a striking rise in the incidence of oesophageal\ud adenocarcinoma, especially in the Western hemisphere, which is only\ud partly understood (“challenge to prevent”).\ud This thesis includes clinical studies that address these issues which\ud are still present in treating this devastating disease

Topics: Oesophageal Cancer
Year: 2015
OAI identifier: oai:repub.eur.nl:79352

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