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Postpandemic influenza A/H1N1pdm09 is still causing severe perinatal complications

By H. (Hein) Bogers, D. (Dominique) Bos, S. (Sam) Schoenmakers and J.J. (Hans) Duvekot


Although influenza A/H1N1pdm09 is not causing a pandemic anymore, we recently observed two critically ill pregnant women infected by this virus. We present these cases to illustrate the possible severe complications of an - at that moment - seasonal influenza in pregnancy. We discuss the epidemiological differences between the pandemic and post pandemic phase and try to explain the high virulence of influenza A/H1N1pdm09 -infections in pregnancy by discussing insights in immunology during pregnancy. We conclude that although influenza A/H1N1pdm09 is in the post pandemic phase, infection by this influenza virus still needs to be considered in pregnant women with progressive respiratory dysfunction

Year: 2015
DOI identifier: 10.4084/mjhid.2015.007
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