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Comparison of solid-state-cultured and wood-cultured Antrodia camphorata in anti-inflammatory effects using NF-κB/luciferase inducible transgenic mice

By Yu-Tang Tung, Tung-Chou Tsai, Yueh-Hsiung Kuo, Chih-Ching Yen, Jheng-Yue Sun, Wen-Hui Chang, Hsiao-Ling Chen and Chuan-Mu Chen


Antrodia camphorata (AC), a highly valued polypore mushroom native only to Taiwan, has been traditionally used as a medicine for the treatment of food and drug intoxication, diarrhea, abdominal pain, hypertension, skin itching, and cancer. In this study, both of solid-state-cultured AC (S-AC) and wood-cultured AC (W-AC) were evaluated the anti-inflammatory effects on hyperoxia-induced lung injury in NF-κB-luciferase(+/+) transgenic mice

Topics: Acute lung injury, Antrodia camphorata, Hyperoxia-induced inflammatory responses, NF-κB-luciferase(+/+) transgenic mice, Solid-state-cultured mycelia, Wood-cultured fruiting bodies, Animals, Anti-Inflammatory Agents, Antrodia, Cytokines, Hyperoxia, I-kappa B Kinase, Lung, Mice, Transgenic, Mycelium, NF-kappa B, Nitric Oxide Synthase Type II, Wood
Year: 2015
DOI identifier: 10.1016/j.phymed.2014.08.011
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