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Receptive language disorder in childhood: Familial aspects and long term outcomes: Results from a Scottish study

By Ann Clark, Anne O'Hare, Jocelynne Watson, W Cohen, H Cowie, R Elton, J Nasir and J Seckl


Background and aims: Little is known about the familial characteristics of children with severe receptive specific language impairment (SLI). Affected children are more likely to have long-term problems than those with expressive SLI but to date they have only been described as small cohorts within SLI populations. We therefore aimed to describe the clinical and familial characteristics of severe receptive SLI as defined by a rigorous phenotype and to establish whether non-word repetition showed a relationship with language impairment in these families. \ud \ud Methods: Cross-sectional study of children who met ICD-10 (F80.2) criteria for receptive SLI at school entry, their siblings and genetic parents with standardised measures of language and non-verbal IQ, phonological auditory memory and speech sound inventory. \ud \ud Results: At a mean of 6 years after school entry with a severe receptive SLI, the 58 participants had a normal mean and standard deviation non-verbal IQ, but only 3% (two) had attained language measures in the normal range. One third still had severe receptive language impairment. One third of siblings not known to be affected had language levels outside the normal range. Phonological auditory memory was impaired in most family members. \ud \ud Conclusion: Severe receptive SLI is nearly always associated with an equally severe reduction in expressive language skills. Language impairment in siblings may go undetected and yet they are at high risk. Family members had weak phonological auditory memory skills, suggesting that this could be a marker for language acquisition difficulties. Receptive SLI rarely resolves and trials of therapy are urgently needed

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  10. Family genetic studies. doi
  11. Follow-up of children attending infant language units: outcomes at 11 years of age. doi
  12. (1999). Fourteen-year follow-up of children with and without speech/language impairments: speech/language stability and outcomes. doi
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  18. Localisation of a gene implicated in a severe speech and language disorder. doi
  19. Non-verbal cognitive development and language impairment. doi
  20. Nonword repetition and word learning: the nature of the relationship. doi
  21. (1996). Nonword repetition as a behavioural marker for inherited language impairment: evidence from a twin study. doi
  22. (1998). Normative Scottish data on the CELF-R UK: a pilot study. doi
  23. Organization. International Statistical Classification of Diseases and Related Health Problems: diagnostic criteria for research, tenth revision (ICD- doi
  24. (1996). Practitioner review of developmental language disorders: a clinical update. doi
  25. (1999). Present and future possibilities for defining a phenotype for a specific language impairment. doi
  26. Prevalence of specific language impairment in kindergarten children. doi
  27. Prevalence of speech delay in 6 year old children and comorbidity with language impairment. doi
  28. Prospective study of development of infants born to mothers with epilepsy.
  29. Psycholinguistic markers for specific language impairment (SLI). doi
  30. (1987). Reynell Developmental Language Scales II. doi
  31. (1998). Screening for speech and language delay: a systematic review of the literature. Health Technol Assess doi
  32. Specific Language Impairment as a maturation lag: evidence from language and motor development. doi
  33. (1995). Specific language impairment: preliminary investigation of factors associated with family history and with patterns of language performance. doi
  34. (2003). Speech and language therapy interventions for children with primary speech and language delay or disorder (Cochrane Review). In: doi
  35. (1996). Standard progressive matrices. doi
  36. (1999). Tager-FlusbergH,CooperJ.Present andfuturepossibilitiesfordefiningaphenotype for a specific language impairment.
  37. (1981). Tallal RP. Selection of children with specific language deficits. doi
  38. (1994). The children’s test of nonword repetition: a test of phonological working memory. doi
  39. (1971). The Edinburgh Articulation Test textbook.
  40. The SLI Consortium (SLIC). Highly significant linkage to SLI1 locus in expanded sample of individuals affected by a specific language impairment. doi
  41. The SLI Consortium. A genomewide scan identifies two novel loci involved in specific language impairment. doi
  42. (1991). Very-low-birthweight children and speech and language development. doi
  43. (1993). World Health Organization, doi

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