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Pathophysiology of subendocardial ischaemia.

By J I Hoffman and G D Buckberg

Abstract

Most forms of heart disease cause myocardial damage which often is confined to the deep (subendocardial) layer of left ventricular muscle. Much clinical and experimental evidence suggests that subendocardial muscle is prone to ischaemic damage, and a physiological mechanism for this vulnerability is described. Furthermore, experiments suggest that pressures recorded at cardiac catheterization can help to assess if there is subendocardial ischaemia in a variety of lesions in man

Topics: Research Article
OAI identifier: oai:pubmedcentral.nih.gov:1672233
Provided by: PubMed Central
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