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Effect of phenmetrazine, aminorex and (±) p-chloramphetamine on the motor activity and turnover rate of brain catecholamines

By E. Costa, K. M. Naimzada and A. Revuelta


1. The minimal doses (μmol/kg i.v.) of phenmetrazine, (±)-p-chloramphetamine, and aminorex which increase motor activity are 5·6, 3·5, and 1·5, respectively. We detected stereotype behaviour neither in rats receiving intravenous doses 3 times greater nor in animals injected intraperitoneally with 44, 62 and 112 μmol/kg of (±)-p-chloramphetamine, aminorex and phenmatrazine, respectively

Topics: Pharmacokinetics
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Provided by: PubMed Central
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