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Contribuicao para o estudo da intervencao metabolica do clenbuterol em ratos submetidos a diferentes niveis alimentares

By Luis Granger Alfaro Cardoso


The effect of the B_2-agonist Clenbuterol on some parameters of the N and energy metabolism was studied in rats submitted to adlibitum diets, 80% and 140% of the maintenance requirements diets. The following results can be emphasized: On treated animals, Clenbuterol did not effect food ingestion; it increased body growing and carcass dressing particularly in food restricted rats; it increased food convention and carcass protein gains; it increased N balances, NPU and VB of alimentary protein in food restricted animals; it increased total amino acid contents of gastrocnemius, with emphasis in the sulphur ones; it increased energy balances, gross energy efficiency and decreased heat increment in diet restricted animals; it induced hypoglycemia, hypoinsulinemia, it did not change T_3, T_4 and testosterone and increased ILGF-1 seric levels; the B_2-agonist preserved the intestinal epithelium morpho-physiology in the diet restricted rats. From these results it is shown that the effects of Clenbuterol are more evident and persistent in the diet restricted ratsAvailable from Fundacao para a Ciencia e a Tecnologia, Servico de Informacao e Documentacao, Av. D. Carlos I, 126, 1200 Lisboa / FCT - Fundação para o Ciência e a TecnologiaSIGLEPTPortuga

Topics: 02G - Veterinary sciences, veterinary medicine, WEIGHT INDICATORS, RATS, FOOD COMPOSITION, DIETS, METABOLISM
Year: 1993
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Provided by: OpenGrey Repository
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